Nonzero Risk of Hepatocellular Carcinoma Even after Sustained Virological Response

Approximately 130 to 150 million people are chronically infected with hepatitis C virus (HCV) in the world. HCV infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC). The existence of hepatitis C— originally identifiable only as a type of non-A, non-B hepatitis— was suggested in the 1970s and proven in 1989. In the treatment of chronic hepatitis C (...

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Risk of hepatocellular carcinoma after sustained virological response in Veterans with hepatitis C virus infection.

UNLABELLED The long-term prognosis in terms of risk or predictors of developing hepatocellular carcinoma (HCC) among patients with sustained virological response (SVR) remains unclear. We conducted a retrospective cohort study using data from the Veterans Affairs VA hepatitis C virus (HCV) Clinical Case Registry in patients with positive HCV RNA between October 1999 and August 2009 and follow-u...

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Risk of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Who Achieved Sustained Virological Response

The recent development of interferon-free direct-acting antivirals (DAAs) has had a significant impact on the already great advances made in the treatment of hepatitis C. Combination therapy with pegylated interferon, ribavirin and simeprevir has achieved a sustained virological response (SVR) rate of approximately 70% in patients with hepatitis C caused by the genotype Ib virus. Combination th...

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Risk of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Who Achieved Sustained Virological Response.

The recent development of interferon-free direct-acting antivirals (DAAs) has had a significant impact on the already great advances made in the treatment of hepatitis C. Combination therapy with pegylated interferon, ribavirin and simeprevir has achieved a sustained virological response (SVR) rate of approximately 70% in patients with hepatitis C caused by the genotype Ib virus. Combination th...

متن کامل

Risk of Hepatocellular Carcinoma in Patients with Hepatitis C Virus Who Achieved Sustained Virological Response

The recent development of interferon-free direct-acting antivirals (DAAs) has had a significant impact on the already great advances made in the treatment of hepatitis C. Combination therapy with pegylated interferon, ribavirin and simeprevir has achieved a sustained virological response (SVR) rate of approximately 70% in patients with hepatitis C caused by the genotype Ib virus. Combination th...

متن کامل

Nonzero Risk of Hepatocellular Carcinoma Even after Sustained Virological Response

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